Ophelia Brown, 17, uses a wheelchair due to the complex regional pain syndrome that she was diagnosed with at nine years old.
When she saw the Interview magazine image of Jenner, Brown was upset and wrote a message on Twitter that was directed at Kylie.
"Having an able-bodied person pose in a wheelchair like it's a fashion accessory, it trivializes the concept of a wheelchair," Brown told CBC News in an interview at her school Thursday.
"A wheelchair is not a fashion accessory, it's not a prop, it's not something that I can easily get in and out of. It's not something that I want. It's something that I need to get to school, to go out with friends, to live a normal life.
"It's not something to be trivialized."